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LY315920 Varespladib

LY315920 Varespladib 172732-68-2
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Chemical Information
Product name:LY315920 Varespladib Purity:98% min
CAS NO:172732-68-2 Solubility:DMSO : ≥ 32 mg/mL (84.12 mM)
Molecular Formula:C21H20N2O5 Package:Package according to customer requirements
Molecular Weight:380.394 Storage:Store at -20℃
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Varespladib, aslo known as LY315920, is a secreted phospholipase A2 (sPLA2) inhibitor (IC50 = 50 - 750 nM for a range of sPLA2 isoforms). Varespladib reduces atherosclerosis and aneurysm formation in ApoE-/- mice and in guinea pigs. Varespladib significantly reduces the post-ACS inflammatory response in those with and without diabetes. Varespladib may be potentially useful for treatment of coronary artery disease.
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