Solriamfetol hydrochloride

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Chemical Information

Product name：Solriamfetol hydrochloride	Purity：98% min
CAS NO：178429-65-7	Solubility：DMSO : 250 mg/mL (1083.71 mM)
Molecular Formula：C₁₀H₁₅ClN₂O₂	Package：Package according to customer requirements
Molecular Weight：230.691	Storage：Store at -20℃

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Remarks

Solriamfetol hydrochloride (JZP-110 hydrochloride) is an orally active and selective dopamine and norepinephrine reuptake inhibitor with IC50s of 2.9 μM and 4.4 μM for dopamine and norepinephrine transporters, respectively. Solriamfetol hydrochloride has robust wake-promoting effects.

References

[1]. Baladi MG, et al. Characterization of the Neurochemical and Behavioral Effects of Solriamfetol (JZP-110), a Selective Dopamine and Norepinephrine Reuptake Inhibitor. J Pharmacol Exp Ther. 2018 Aug;366(2):367-376.

[2]. Yang J, et al. Solriamfetol for the treatment of excessive daytime sleepiness associated with narcolepsy. Expert Rev Clin Pharmacol. 2019 Aug;12(8):723-728.