BMS-207147 Ravuconazole

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：BMS-207147 Ravuconazole	Purity：99% min
CAS NO：182760-06-1	Solubility：DMSO : ≥ 50 mg/mL (114.29 mM)
Molecular Formula：C₂₂H₁₇F₂N₅OS	Package：Package according to customer requirements
Molecular Weight：437.465	Storage：Store at -20℃

Quality control

Remarks

Ravuconazole (codenamed BMS-207147 and ER-30346) is a potent triazole antifungal, being developed by Bristol-Myers Squibb, that is currently in phase I/II clinical trials. The drug has shown to have a similar spectrum of activity to voriconazole, with an increased half-life. However, ravuconazole has limited activity against species of Fusarium, Scedosporium, and Zygomycetes.

Properties:
Density: 1.38g/cm3
Boiling Point: 674.9ºC at 760 mmHg
Flash Point: 362ºC
Refractive Index: 1.665
Vapor Pressure: 3.89E-19mmHg at 25°C

References

[1]. Hata K, et al. In vitro and in vivo antifungal activities of ER-30346, a novel oral triazole with a broad antifungal spectrum.Antimicrob Agents Chemother. 1996 Oct;40(10):2237-42.

[2]. Fung-Tomc JC, et al. In vitro activity of a new oral triazole, BMS-207147 (ER-30346)Antimicrob Agents Chemother. 1998 Feb;42(2):313-8.