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RG7834 S-isomer

RG7834 S-isomer 2072057-17-9
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Chemical Information
Product name:RG7834 S-isomer Purity:98% min
CAS NO:2072057-17-9 Solubility:
Molecular Formula:C22H27NO6 Package:Package according to customer requirements
Molecular Weight:401.453 Storage:-20 ℃
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Remarks

RG7834 (RO 7020322) is a highly selective and orally bioavailable inhibitor of HBV. RG7834 potently inhibits HBsAg, HBeAg, and HBV DNA, with IC50 of 2.8 nM, 2.6 nM, and 3.2 nM, respectively, in dHepaRG cells.


References
[1]. Han X, et al. Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action. J Med Chem. 2018 Oct 4.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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