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Sitaxsentan sodium

Sitaxsentan sodium 210421-74-2
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Chemical Information
Product name:Sitaxsentan sodium Purity:98% min
CAS NO:210421-74-2 Solubility:H2O: soluble10mg/mL (clear solution)
Molecular Formula:C18H14ClN2NaO6S2 Package:Packaging according to customer requirements
Molecular Weight:476.89 Storage:Store at -20℃
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Sitaxentan, also known as TBC-11251 and IPI 1040, is a medication for the treatment of pulmonary arterial hypertension (PAH). It was marketed as Thelin. In 2010, Pfizer voluntarily removed sitaxentan from the market due to concerns about liver toxicity. Sitaxentan is a small molecule that blocks the action of endothelin (ET) on the endothelin-A (ETA) receptor selectively (by a factor of 6000 compared with the ETB).


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