Product :
Ixabepilone
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Chemical Information
| Product name：Ixabepilone |
Purity：98% min |
| CAS NO：219989-84-1 |
Solubility：DMSO : 83.33 mg/mL (164.46 mM) |
| Molecular Formula：C27H42N2O5S |
Package：Package according to customer requirements. |
| Molecular Weight：506.698 |
Storage：Store at -20℃ |
Remarks
Ixabepilone (also known as azaepothilone B, or BMS-247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Ixabepilone was approved in 2007. Check for active clinical trials or closed clinical trials using this agent.