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ADH-1 Exherin

ADH-1 Exherin 229971-81-7
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Chemical Information
Product name:ADH-1 Exherin Purity:98% min
CAS NO:229971-81-7 Solubility:10 mM in DMSO
Molecular Formula:C24H35F3N8O8S2 Package:Package according to customer requirements
Molecular Weight:684.709 Storage:Store at -20℃
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Remarks
Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. Note: The old CAT# for this product was 201350A
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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