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Fosaprepitant Dimeglumine

Fosaprepitant Dimeglumine 265121-04-8
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Chemical Information
Product name:Fosaprepitant Dimeglumine Purity:98% min
CAS NO:265121-04-8 Solubility:H2O : 50 mg/mL (49.76 mM)
Molecular Formula:C37H56F7N6O16P Package:Package according to customer requirements
Molecular Weight:1004.83 Storage:Store at -20℃
Quality control
COA
Remarks

Fosaprepitant, also known as MK0517, is an antiemetic drug, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. Fosaprepitant is a weak inhibitor of CYP3A4, and aprepitant, the active moiety, is a substrate, inhibitor, and inducer of CYP3A4.

Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).


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