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Nomifensine maleate

Nomifensine maleate 32795-47-4
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Chemical Information
Product name:Nomifensine maleate Purity:98% min
CAS NO:32795-47-4 Solubility:DMSO : ≥ 80 mg/mL (225.73 mM)
Molecular Formula:C20H22N2O4 Package:Package according to customer requirements.
Molecular Weight:354.40 Storage:Store at -20℃
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Remarks

Nomifensine Maleate is a selective dopamine uptake inhibitor interacting with the dopamine transporter at a site different from that of cocaine; antidepressan.

 

Synonyms:

Nomifensine;

8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline maleate (1_1);

1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate salt;

 

Properties:

Density: 1.114g/cm3

Boiling Point: 378.4ºC at 760mmHg

Melting Point: 179-181ºC

Flash Point: 164ºC

Refractive Index: 1.581

 

 

References

1: Taharabaru S, Satomoto M, Tamura T, Adachi YU. Smaller effect of propofol than sevoflurane anesthesia on dopamine turnover induced by methamphetamine and nomifensine in the rat striatum: an in vivo microdialysis study. Exp Anim. 2017 Nov 23. doi: 10.1538/expanim.17-0092. [Epub ahead of print] PubMed PMID: 29176298.

2: Shin M, Field TM, Stucky CS, Furgurson MN, Johnson MA. Ex Vivo Measurement of Electrically Evoked Dopamine Release in Zebrafish Whole Brain. ACS Chem Neurosci. 2017 Sep 20;8(9):1880-1888. doi: 10.1021/acschemneuro.7b00022. Epub 2017 Jun 28. PubMed PMID: 28617576.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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