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UK-383367 348622-88-8
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Chemical Information
Product name:UK-383367 Purity:98% min
CAS NO:348622-88-8 Solubility:10 mM in DMSO
Molecular Formula:C15H24N4O4 Package:Package according to customer requirements
Molecular Weight:324.375 Storage:Store at -20℃
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UK-383367 is a potent and selective inhibitor of BMP-1 (procollagen C-proteinase; PCP) (IC50 = 44 nM). Bone morphogenic protein 1 (BMP1) is an enzyme responsible for the cleavage and maturation of growth factors and ECM proteins. The purpose of our study was to determine whether cultured human trabecular meshwork (TM) cells express BMP1, BMP1 expression is regulated by TGF-β2, BMP1 is biologically active, and BMP1 regulates LOX activity.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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