dimebolin

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：dimebolin	Purity：98% min
CAS NO：3613-73-8	Solubility：Soluble in DMSO
Molecular Formula：C₂₁H₂₅N₃	Package：Package according to customer requirements
Molecular Weight：319.443	Storage：Store at -20℃

Quality control

Remarks

Latrepirdine is an orally-available drug, approved in Russia for use as a non-selective antihistamine, that has shown promise in the treatment of neurodegenerative diseases, including Alzheimer’s and Huntington’s disease. In addition to reported activity in preventing the onset and progression of disease by being neuroprotective, dimebolin appears to promote clinical improvement by increasing cognitive function. At the cellular level, dimebolin appears to have diverse effects, inhibiting the neurotoxic action of β-amyloid and blocking L-type calcium channels,5 inhibiting NMDA-type glutamate receptors, and preventing mitochondrial leakage.

References

1: Chau S, Herrmann N, Ruthirakuhan MT, Chen JJ, Lanctôt KL. Latrepirdine for Alzheimer's disease. Cochrane Database Syst Rev. 2015 Apr 21;(4):CD009524. doi: 10.1002/14651858.CD009524.pub2. Review. PubMed PMID: 25897825.

2: Cano-Cuenca N, Solís-García del Pozo J, Jordán J. [Latrepirdine: a systematic review of the preclinical studies]. Rev Neurol. 2015 Jan 1;60(1):35-42. Review. Spanish. PubMed PMID: 25522862.