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Cinacalcet hydrochloride AMG-073 HCl

Cinacalcet hydrochloride AMG-073 HCl 364782-34-3
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Chemical Information
Product name:Cinacalcet hydrochloride AMG-073 HCl Purity:98% min
CAS NO:364782-34-3 Solubility:DMSO : ≥ 50 mg/mL (126.95 mM)
Molecular Formula:C22H23ClF3N Package:Package according to customer requirements
Molecular Weight:393.873 Storage:Store at -20℃
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Remarks
Cinacalcet Hydrochloride is a type II calcimimetic agent which controls calcium levels in cells by allosteric activation of CaSR. In the presence of calcium ions, it can inhibit parathyroid hormone secretion by activating CaSR in parathyroid glands. Studies show that Cinacalcet Hydrochloride affects cell proliferation in CHO cells transfected with CaSRs. In addition, it is known that Cinacalcet Hydrochloride inhibits the secretion of the parathyroid hormone (PTH). Cinacalcet has been used clinically to treat secondary hyperparathyroidism due to end-stage renal disease or hypercalcemia in patients with parathyroid carcinoma.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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