(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide is an intermediate in the synthesis of Isavuconazole, an triazole based antifungal agent for the treatment of invasive fungal infections.
Chemical Name:
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
Synonyms:
Isavuconazole intermediate 8;
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanethioamide;
Properties:
Boiling point: 536.4±60.0 °C(Predicted)
density: 1.43±0.1 g/cm3(Predicted)
pka: 11.54±0.29(Predicted)
Related Products:
Isavuconazole; Isavuconazole side chain