AKT-I-1

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Chemical Information

Product name：AKT-I-1	Purity：98% min
CAS NO：473382-39-7	Solubility：Soluble in DMSO
Molecular Formula：C₂₂H₃₀N₆	Package：Package according to customer requirements
Molecular Weight：378.514	Storage：Store at -20℃

Quality control

Remarks

AKT-I-1 is a selective reversible inhibitor of Akt1.

References

1: Yamaji M, Ota A, Wahiduzzaman M, Karnan S, Hyodo T, Konishi H, Tsuzuki S, Hosokawa Y, Haniuda M. Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells. Cancer Med. 2017 Nov;6(11):2646-2659. doi: 10.1002/cam4.1179. Epub 2017 Sep 27. PubMed PMID: 28960945; PubMed Central PMCID: PMC5673922.

2: Liebl D, Qi X, Zhe Y, Barnett TC, Teasdale RD. SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell. Front Cell Infect Microbiol. 2017 Jun 15;7:257. doi: 10.3389/fcimb.2017.00257. eCollection 2017. PubMed PMID: 28664153; PubMed Central PMCID: PMC5471308.