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BAN ORL 24

BAN ORL 24 475150-69-7
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Chemical Information
Product name:BAN ORL 24 Purity:98% min
CAS NO:475150-69-7 Solubility:DMSO
Molecular Formula:C27H35N3O2.2HCl Package:Package according to customer requirements
Molecular Weight:506.512 Storage:Store at -20℃
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Remarks

 BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). IC50 value: 0.27 nM Target: NOP receptor BAN ORL 24 inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.

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