Isotretinoin

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Chemical Information

Product name：Isotretinoin	Purity：99% min
CAS NO：4759-48-2	Solubility：DMSO : 100 mg/mL (332.85 mM)
Molecular Formula：C₂₀H₂₈O₂	Package：Package according to customer requirements
Molecular Weight：300.435	Storage：Store at -20℃

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Remarks

Isotretinoin is a topical dermatologic agent that is used in the treatment of acne and several other skin diseases. It may also treat depression and anxiety. The drug has teratogenic and other adverse effects.

Properties:
Appearance & Physical State: yellowish crystalline powder
Density: 1.011 g/cm3
Melting Point: 174-177ºC
Boiling Point: 462.8ºC at 760 mmHg
Flash Point: 350.6ºC
Water Solubility: insoluble
Stability: Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
Storage Condition: -20ºC

References

[1]. Thielitz, A. and H. Gollnick, [Isotretinoin. How should it be used?]. Hautarzt, 2013. 64(4): p. 263-8.

[2]. Norris, D.A., et al., Isotretinoin produces significant inhibition of monocyte and neutrophil chemotaxis in vivo in patients with cystic acne. J Invest Dermatol, 1987. 89(1): p. 38-43.