Isoindigotin

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Chemical Information

Product name：Isoindigotin	Purity：98% min
CAS NO：476-34-6	Solubility：
Molecular Formula：C₁₆H₁₀N₂O₂	Package：Package according to customer requirements
Molecular Weight：262.263	Storage：Store at -20℃

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Remarks

Isoindigo has proven successful as an electron-accepting building block for the preparation of electroactive materials for organic electronics. Meisoindigo, as a functionalized Isoindigo, has been used as an indirubin substitute for the treatment of chronic myeloid leukemia (CML).

Properties:
Density: 1.417g/cm3
Boiling Point: 576.3ºC at 760mmHg
Flash Point: 245.1ºC
Refractive Index: 1.709
Vapor Pressure: 2.79E-13mmHg at 25°C

References

1: Wu KM, Zhang MY, Fang Z, Huang L. [Potential antileukemic agents, synthesis of derivatives of indirubin, indigo, and isoindigotin]. Yao Xue Xue Bao. 1985 Nov;20(11):821-6. Chinese. PubMed PMID: 3869774.

2: Saleh AM, Aljada A, El-Abadelah MM, Sabri SS, Zahra JA, Nasr A, Aziz MA. The pyridone-annelated isoindigo (5'-Cl) induces apoptosis, dysregulation of mitochondria and formation of ROS in leukemic HL-60 cells. Cell Physiol Biochem. 2015;35(5):1958-74. doi: 10.1159/000374004. PubMed PMID: 25871324.