Product :
ZLN005
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Chemical Information
Product name:ZLN005 |
Purity:98% min |
CAS NO:49671-76-3 |
Solubility:DMSO : ≥ 47 mg/mL (187.74 mM) |
Molecular Formula:C17H18N2 |
Package:Package according to customer requirements |
Molecular Weight:250.338 |
Storage:Store at -20℃ |
Remarks
ZLN005 is a PGC-1α Transcriptional Regulator, which shoed some beneficialfEffects on diabetic db/db mice. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice. Hyperglycemia and dyslipidemia also were ameliorated after treatment with ZLN005. Our results demonstrated that a novel small molecule selectively elevated the expression of PGC-1α in myotubes and skeletal muscle and exerted promising therapeutic effects for treating type 2 diabetes.