KX1-004

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Chemical Information

Product name：KX1-004	Purity：98% min
CAS NO：518058-84-9	Solubility：DMSO : ≥ 42 mg/mL (147.74 mM)
Molecular Formula：C₁₆H₁₃FN₂O₂	Package：Package according to customer requirements
Molecular Weight：294.369	Storage：Store at -20℃

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Remarks

KX1-004 is an Src-protein tyrosine kinase inhibitor to reduce cisplatin ototoxicity while preserving its antitumor effect. KX1-004 has been used to protect the cochlea from hazardous noise.

References

[1]. Harris KC, et al. Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct;208(1-2):14-25.

[2]. Bielefeld EC, et al. A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss. Noise Health. 2005 Oct-Dec;7(29):24-30.