Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. Vigabatrin is an irreversible suicide inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the catabolism of GABA, which increases the level of GABA in the brain. Vigabatrin is a racemic compound, and its [S]-enantiomer is pharmacologically active.
Properties:
Density: 1.108 g/mL at 25 °C(lit.)
Boiling Point: 73 °C749 mm Hg(lit.)
Flash Point: 16 °F
Refractive Index: n20/D 1.319(lit.)
Storage Condition: Desiccate at +4ºC