Product :
LH846
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Chemical Information
Product name:LH846 |
Purity:98% min |
CAS NO:639052-78-1 |
Solubility:DMSO : ≥ 45 mg/mL (142.04 mM) |
Molecular Formula:C16H13ClN2OS |
Package:Package according to customer requirements |
Molecular Weight:316.805 |
Storage:Store at -20℃ |
Remarks
LH846 is a selective inhibitor of casein kinase. IC50 values of LH846 are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α). LH 846 has been shown to inhibit CK1δ-dependent phosphorylation and degradation of PER1 protein and to lengthen the circadian period in U2OS cells.