Norethindrone

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Chemical Information

Product name：Norethindrone	Purity：98% min
CAS NO：68-22-4	Solubility：DMSO : 110 mg/mL (368.61 mM)
Molecular Formula：C₂₀H₂₆O₂	Package：Package according to customer requirements.
Molecular Weight：298.419	Storage：Store at -20℃

Quality control

COA

Remarks

Norethindrone is a steroidal progestin used in some combined oral contraceptive pills and progestogen-only pills, and is also available as a standalone drug. It can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with estrogen), or to postpone a period. It is also commonly used to help prevent uterine hemorrhage in complicated non-surgical or pre-surgical gynecologic cases and in treating non responsive cyclical mastalgia. Norethisterone was the first orally highly active progestin to be synthesized.

References

1: Chwalisz K, Surrey E, Stanczyk FZ. The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis. Reprod Sci. 2012 Jun;19(6):563-71. doi: 10.1177/1933719112438061. Epub 2012 Mar 27. Review. PubMed PMID: 22457429.

2: Casey CL, Murray CA. HT update: spotlight on estradiol/norethindrone acetate combination therapy. Clin Interv Aging. 2008;3(1):9-16. Review. PubMed PMID: 18488874; PubMed Central PMCID: PMC2544373.