Ivermectin (MK-933)

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Chemical Information

Product name：Ivermectin (MK-933)	Purity：98% min
CAS NO：70288-86-7	Solubility：DMSO : ≥ 50 mg/mL (57.14 mM)
Molecular Formula：C₄₈H₇₄O₁₄	Package：Package according to customer requirements
Molecular Weight：875.093	Storage：Store at -20℃

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Remarks

Ivermectin is a medication that is effective against many types of parasites. It is used to treat head lice, scabies, river blindness, strongyloidiasis, and lymphatic filariasis, among others. Ivermectin and other avermectins (insecticides most frequently used in home-use ant baits) are macrocyclic lactones derived from the bacterium Streptomyces avermitilis. Ivermectin kills by interfering with nervous system and muscle function, in particular by enhancing inhibitory neurotransmission. Ivermectin is a mixture of mostly avermectin H2B1a (CAS# 71827-03-7) with some avermectin H2B1b (CAS# 70209-81-3), which are macrolides from STREPTOMYCES avermitilis.

Chloride Channel Inhibitors Related Prodcuts:

Torasemide; Fluralaner; Lubiprostone

References

[1]. Khakh BS, et al. Allosteric control of gating and kinetics at P2X(4) receptor channels. J Neurosci. 1999 Sep 1;19(17):7289-99.

[2]. Priel A, et al. Mechanism of ivermectin facilitation of human P2X4 receptor channels. J Gen Physiol. 2004 Mar;123(3):281-93.