Remodulin Treprostinil

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Chemical Information

Product name：Remodulin Treprostinil	Purity：98% min
CAS NO：81846-19-7	Solubility：DMSO : ≥ 125 mg/mL (320.09 mM)
Molecular Formula：C₂₃H₃₄O₅	Package：Package according to customer requirements.
Molecular Weight：390.52	Storage：Store at -20℃

Quality control

COA

Remarks

Treprostinil is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a synthetic analog of prostacyclin (PGI2). The inhaled form of treprostinil was approved by the FDA in July 2009.

Properties:

Density: 1.158g/cm3

Boiling Point: 587.1ºC at 760mmHg

Flash Point: 199.3ºC

Refractive Index: 1.553

Prostaglandins Related Products:

TP-2(TV-EDI); Misoprostol; Ornoprostil; Epoprostenol sodium; Treprostinil sodium; Unoprostone; Isopropyl unoprostone; Cyclopropyl methyl amide; Etiproston ; PPB-lactondiol

References

[1]. Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist. Biochem Pharmacol. 2012 Jul 1;84(1):68-75.

[2]. Ferrantino M, et al. Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2011 Nov;12(16):2583-93.

[3]. Ghonem N, et al. Treprostinil, a prostacyclin analog, ameliorates ischemia-reperfusion injury in rat orthotopic liver transplantation. Am J Transplant. 2011 Nov;11(11):2508-16.