Product :
AZ-13337019 NKTR-118 Naloxegol
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Chemical Information
| Product name：AZ-13337019 NKTR-118 Naloxegol |
Purity：99% min |
| CAS NO：854601-70-0 |
Solubility：Soluble in DMSO |
| Molecular Formula：C34H53NO11 |
Package：Package according to customer requirements |
| Molecular Weight：651.785 |
Storage：Store at -20℃ |
Remarks
Naloxegol, also known as and NKTR-118 and AZ-13337019, is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. It was approved in 2014 in adult patients with chronic, non-cancer pain. Chemically, naloxegol is a pegylated (polyethylene glycol-modified) derivative of α-naloxol. Specifically, the 5-α-hydroxyl group of α-naloxol is connected via an ether linkage to the free hydroxyl group of a monomethoxy-terminated n=7 oligomer of PEG.