Takeda103A

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Chemical Information

Product name：Takeda103A	Purity：98% min
CAS NO：865609-72-9	Solubility：
Molecular Formula：C₂₄H₂₃F₂N₇O	Package：Package according to customer requirements
Molecular Weight：463.483	Storage：-20 ℃

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Remarks

Takeda103A is a potent GRK2-dependent bovine tubulin oxidation inhibitor.

References

1: Waldschmidt HV, Homan KT, Cruz-Rodríguez O, Cato MC, Waninger-Saroni J, Larimore KM, Cannavo A, Song J, Cheung JY, Kirchhoff PD, Koch WJ, Tesmer JJ, Larsen SD. Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J Med Chem. 2016 Apr 28;59(8):3793-807. doi: 10.1021/acs.jmedchem.5b02000. Epub 2016 Apr 13. PubMed PMID: 27050625; PubMed Central PMCID: PMC4890168.