Product :
SL25.1188
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Chemical Information
| Product name：SL25.1188 |
Purity：98% min |
| CAS NO：876746-56-4 |
Solubility：DMSO |
| Molecular Formula：C16H17F3N2O5 |
Package：Package according to customer requirements |
| Molecular Weight：374.312 |
Storage：Store at -20℃ |
Remarks
L-25.1188 is a monoamine oxidase B (MAO-B) inhibitor potentially for treatment of Alzheimer's dementia and smoking cessation. SL-25.1188 is characterized in vivo by reversible binding, high brain uptake, and very slow plasma metabolism.
References
1: Saba W, Valette H, Peyronneau MA, Bramoullé Y, Coulon C, Curet O, George P, Dollé F, Bottlaender M. [(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64(1):61-9. doi: 10.1002/syn.20703. PubMed PMID: 19728365.