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INNO-406 Bafetinib

INNO-406 Bafetinib 887650-05-7
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Chemical Information
Product name:INNO-406 Bafetinib Purity:98% min
CAS NO:887650-05-7 Solubility:10 mM in DMSO
Molecular Formula:C30H31F3N8O Package:Package according to customer requirements
Molecular Weight:576.615 Storage:Store at -20℃
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Bafetinib, also known as INNO-406 and NS187, is an orally bioavailable 2-phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr/Abl fusion protein tyrosine kinase, an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML). This agent also inhibits the Src-family member Lyn tyrosine kinase, upregulated in imatinib-resistant CML cells and in a variety of solid cancer cell types.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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