Aprotinin

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Chemical Information

Product name：Aprotinin	Purity：99% min
CAS NO：9087-70-1	Solubility：H2O : 100 mg/mL (15.36 mM)
Molecular Formula：C₂₈₄H₄₃₂N₈₄O₇₈R₂S₇	Package：Package according to customer requirements
Molecular Weight：6495.43988	Storage：Store at -20℃

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Remarks

Aprotinin is a small protein serine protease inhibitor (Kd=0.06 pM for bovine β-trypsin), used to reduce perioperative blood loss and transfusion.

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References

[1]. Fritz H, et al. Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs. Arzneimittelforschung. 1983;33(4):479-94.

[2]. Levy JH, et al. Efficacy and safety of aprotinin in cardiac surgery. Orthopedics. 2004 Jun;27(6 Suppl):s659-62.

[3]. Venturini G, et al. Aprotinin, the first competitive protein inhibitor of NOS activity. Biochem Biophys Res Commun. 1998 Aug 10;249(1):263-5