Product :
Radotinib IY 5511
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Chemical Information
| Product name：Radotinib IY 5511 |
Purity：99% min |
| CAS NO：926037-48-1 |
Solubility：DMSO : ≥ 38 mg/mL (71.63 mM) |
| Molecular Formula：C27H21F3N8O |
Package：Package according to customer requirements |
| Molecular Weight：530.504 |
Storage：Store at -20℃ |
Remarks
Radotinib, also known as IY-5511, is an orally available, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways.