Cefprozil, under the marketed trade name Cefzil, is a second-generation cephalosporin type antibiotic. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation.
Properties
Appearance & Physical State: white to yellow crystalline powder
Density: 1.53g/cm3
Melting Point: 76°C
Boiling Point: 803.1ºC at 760mmHg
Flash Point: 439.5ºC
Refractive Index: 1.718
Vapor Pressure: 0mmHg at 25°C