BMS-303141

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Chemical Information

Product name：BMS-303141	Purity：98% min
CAS NO：943962-47-8	Solubility：DMSO : ≥ 47 mg/mL (110.77 mM)
Molecular Formula：C₁₉H₁₅Cl₂NO₄S	Package：Package according to customer requirements
Molecular Weight：424.298	Storage：Store at -20℃

Quality control

Remarks

BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.

Properties:

Boiling point: 591.5±60.0 °C(Predicted)

solubility DMSO: soluble20mg/mL, clear

form: powder

pka: 4.94±0.48(Predicted)

color: white to beige

ATP-citrate lyase inhibitor Related Products:

Bempedoic acid

References

[1]. Li JJ, et al. 2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3208-11.