Sotalol hydrochloride

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Chemical Information

Product name：Sotalol hydrochloride	Purity：98% min
CAS NO：959-24-0	Solubility：DMSO : ≥ 30 mg/mL (97.14 mM)
Molecular Formula：C₁₂H₂₁ClN₂O₃S	Package：Package according to customer requirements
Molecular Weight：308.825	Storage：Store at -20℃

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Remarks

Sotalol hydrochloride is an adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.Sotalol hydrochloride is a compound categorized with class III antiarrhythmic activity with a mechanism of action that prolongs the action potential and refraction of cardiac tissue through non-selective yet potent β-adronergic blocking activity.

Properties:
Appearance & Physical State: white to off-white powder
Melting Point: 218-220ºC
Boiling Point: 443.3ºC at 760 mmHg
Flash Point: 221.9ºC

Adrenergic Receptor Inhibitors Related Products:

Nebivolol hydrochloride; Nebivolol; Betaxolol; Betaxolol HCl; Doxazosin Mesylate; Alfuzosin HCl; Silodosin; Prazosin Hydrochloride; Terazosin hydrochloride dihydrate; Dapiprazole Hydrochloride; Cisatracurium besylate; Ivabradine hydrochloride ; Vilanterol Trifenate

References

[1]. Antonaccio, M.J. and A. Gomoll, Pharmacologic basis of the antiarrhythmic and hemodynamic effects of sotalol. Am J Cardiol, 1993. 72(4): p. 27A-37A.

[2]. Bertrix, L., et al., Protection against ventricular and atrial fibrillation by sotalol. Cardiovasc Res, 1986. 20(5): p. 358-63.