N-Methylisoindigotin Meisoindigo

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Chemical Information

Product name：N-Methylisoindigotin Meisoindigo	Purity：98% min
CAS NO：97207-47-1	Solubility：DMSO : ≥ 51 mg/mL (184.59 mM)
Molecular Formula：C₁₇H₁₂N₂O₂	Package：Package according to customer requirements
Molecular Weight：276.289	Storage：Store at -20℃

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Remarks

Meisoindigo, also known as N-Methylisoindigotin and Dian III, is an apoptosis inducer and potential agent for AML. Meisoindigo has been a routine therapeutic agent in the clinical treatment of chronic myelogenous leukemia (CML) in China since the 1980s. Meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia.

Properties:

Density: 1.381 g/cm3

Melting Point: 236-237ºC

Boiling Point: 482ºC at 760 mmHg

Flash Point: 245.3ºC

Refractive Index: 1.698

References

[1]. Lee CC, et al. Meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia. Leuk Lymphoma. 2010 May;51(5):897-905.

[2]. Mingxin Z, et al. The antitumor activity of meisoindigo against human colorectal cancer HT-29 cells in vitro and in vivo. J Chemother. 2008 Dec;20(6):728-33.