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AZ32 unknown
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Chemical Information
Product name:AZ32 Purity:98% min
CAS NO:unknown Solubility:Soluble in DMSO
Molecular Formula:C20H16N4O Package:Package according to customer requirements
Molecular Weight:328.375 Storage:Store at -20℃
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AZ32 is an orally bioavailable and blood-brain-barrier penetrating ATM inhibitor (AZ32) that radiosensitizes intracranial gliomas in mice. AZ32 was highly efficient in vivo as radiosensitizer in syngeneic and human, orthotopic mouse glioma model compared with AZ31. AZ32 is the first ATMi with oral bioavailability shown to radiosensitize glioma and improve survival in orthotopic mouse models.
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