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Dolutegravir GSK1349572

Dolutegravir GSK1349572  1051375-16-6
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Chemical Information
Product name:Dolutegravir GSK1349572 Purity:98% min
CAS NO:1051375-16-6 Solubility:DMSO : 10 mg/mL (23.84 mM)
Molecular Formula:C20H19F2N3O5 Package:Package according to customer requirements
Molecular Weight:419.38 Storage:Store at -20℃
Quality control
Dolutegravir, also known as GSK1349572, is a potent inhibitor of HIV integrase with an IC50 value of 2.7 nM for HIV-1 integrase-catalyzed strand transfer in vitro.1 It inhibits HIV-1 viral replication (EC50 = 0.51 nM) in peripheral blood mononuclear cells (PBMCs). Dolutegravir (DTG) is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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