Pneumocandin B0(L-688786), a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance.
It is a strong antifungal and inhibits the synthesis of beta-(1,3)-D-glucan, which is a fundamental component in most cell walls, like the Candida Albans membrane. This is a very important activity since there is an increase in the frequency of fungal infections, accompanied by an increase in the variety of opportunistic and pathogenic fungi like Candida. This compound is used to synthesize caspofungin.[full citation needed]; Pneumocandin B0 can be easily confused with Pneumocandin B, although they have different kind of chains and residues.
Chemical Properties:
Boiling point: 1442.9±65.0 °C(Predicted)
density: 1.41±0.1 g/cm3(Predicted)
pka: 9.86±0.26(Predicted)
λmax: 276nm(MeOH)(lit.)
Related Prodcuts:
Echinocandin B; ECBN HCL; Micafungin sodium; Micafungin FR-179642; Caspofungin Acetate; Caspofungin; Anidulafungin