GNE-0877 is a highly potent and selective LRRK2 inhibitor. Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in the neuroscience research community because it is one of the most compelling targets for a potential disease-modifying Parkinson's disease therapy.
Chemical Name:
1H-Pyrazole-1-acetonitrile, α,α,3-trimethyl-4-[[4-(methylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-
Chemical Properties:
Boiling point: 506.3±60.0 °C(Predicted)
density: 1.36±0.1 g/cm3(Predicted)
pka: 3.87±0.10(Predicted)
LRRK2 Inhibitors Related Products:
PF06447475; GSK2578215A; URMC-099; LRRK2-IN-1