Celecoxib

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Chemical Information

Product name：Celecoxib	Purity：98% min
CAS NO：169590-42-5	Solubility：DMSO : ≥ 50 mg/mL (131.11 mM)
Molecular Formula：C₁₇H₁₄F₃N₃O₂S	Package：Package according to customer requirements.
Molecular Weight：381.372	Storage：Store at -20℃

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Remarks

Celecoxib, also known as SC-58635 and YM-177, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older.

COX Inhibitors Related Products:

Resveratrol; Indomethacin; Lornoxicam; Amfenac Sodium Monohydrate; S-ketoprofen; Meloxicam; Aspirin; Suprofen; Etodolac; Licofelone; ATB-346; FK3311; Deracoxib; Parecoxib; Piroxicam

References

[1]. Penning TD, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem. 1997

[2]. Liu DB, et al. Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. Acta Pharmacol Sin. 2012 May;33(5):682-90.

[3]. Suri A, et al. The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer. Oncotarget. 2016 Apr 8.