Elimusertib (BAY-1895344)

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：Elimusertib (BAY-1895344)	Purity：98% min
CAS NO：1876467-74-1	Solubility：DMSO : 5.4 mg/mL (14.38 mM)
Molecular Formula：C₂₀H₂₁N₇O	Package：Package according to customer requirements.
Molecular Weight：375.427	Storage：Store at -20℃

Quality control

Remarks

Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib has anti-tumor activity. Elimusertib can be used for the research of solid tumors and lymphomas.

ATM/ATR Inhibitors Related Products:

Dactolisib; KU-55933; Wortmannin; CP-466722; AZ32; Mirin; KU-60019

References

[1]. Ulrich T. Luecking, et al. Abstract 983: Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement.

[2]. Antje Margret Wengner, et al. Abstract 836: ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement