Fumagillin

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Chemical Information

Product name：Fumagillin	Purity：99% min
CAS NO：23110-15-8	Solubility：92 mg/mL (200.63 mM)
Molecular Formula：C₂₆H₃₄O₇	Package：Package according to customer requirements
Molecular Weight：458.544	Storage：Store at -20℃

Quality control

COA

Remarks

Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus. Fumagillin has been used in the treatment of microsporidiosis. It is also an amebicide. Fumagillin can block blood vessel formation by binding to an enzyme methionine aminopeptidase and for this reason, the compound, together with semisynthetic derivatives, are investigated as an angiogenesis inhibitor in the treatment of cancer.

Properties:

Appearance & Physical State:Light yellow solid

Density:1.19g/cm3

Boiling Point: 608.8ºC at 760mmHg

Melting Point: >190ºC-192ºC

Flash Point: 198.8ºC

Refractive Index: 1.562

Vapor Pressure: 2.7E-16mmHg at 25°C

Related Prodcuts:

Doramectin; Spinosad; Moxidectin; Milbemycin oxime; Imidacloprid; Trilostane; Pimobendan; Maropitant Citrate; Fluralaner; Afoxolaner; Tiamulin famarate; Selamectin

References

[1]. Lefkove, B., B. Govindarajan, and J.L. Arbiser, Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther, 2007. 5(4): p. 573-9.