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Somatostatin Acetate

Somatostatin Acetate 38916-34-6
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Chemical Information
Product name:Somatostatin Acetate Purity:98% min
CAS NO:38916-34-6 Solubility:H2O : 71.3 mg/mL (43.53 mM)
Molecular Formula:C76H104N18O19S2 Package:Package according to customer requirements
Molecular Weight:1637.88 Storage:Store at -20℃
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Remarks

Somatostatin, also known as growth hormone–inhibiting hormone (GHIH), is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids (shown in infobox to right), the other of 28 amino acids which is the short form with another 14 amino acids at one end.

 

 

 

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References

1: Virgolini I, Gabriel M, Kroiss A, von Guggenberg E, Prommegger R, Warwitz B, Nilica B, Roig LG, Rodrigues M, Uprimny C. Current knowledge on the sensitivity of the (68)Ga-somatostatin receptor positron emission tomography and the SUV(max) reference range for management of pancreatic neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2016 May 13. [Epub ahead of print] Review. PubMed PMID: 27174220.

2: Tartarone A, Lerose R, Aieta M. Somatostatin Analog Therapy in Small Cell Lung Cancer. Semin Nucl Med. 2016 May;46(3):239-42. doi: 10.1053/j.semnuclmed.2015.12.004. Review. PubMed PMID: 27067504.

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