Bezafibrate

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Chemical Information

Product name：Bezafibrate	Purity：98% min
CAS NO：41859-67-0	Solubility：DMSO : ≥ 50 mg/mL (138.19 mM)
Molecular Formula：C₁₉H₂₀ClNO₄	Package：Package according to customer requirements
Molecular Weight：361.819	Storage： Store at -20℃

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Remarks

Bezafibrate is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha) with antilipidemic activity. Bezafibrate is a fibrate drug used for the treatment of hyperlipidaemia. Bezafibrate decreases triglyceride levels, increases high density lipoprotein cholesterol levels, and decreases total and low density lipoprotein cholesterol levels. It is commonly marketed as Bezalip.

Properties:
Appearance & Physical State: solid
Density: 1.26 g/cm3
Melting Point: 184ºC
Boiling Point: 572.1ºC at 760 mmHg
Flash Point: 299.8ºC
Refractive Index: 1.583

PPAR Inhibitors Related Prodcuts:

GW9662; GSK3787; Fenofibric acid

References

[1]. Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50.

[2]. Usui-Ouchi A, et al. The peroxisome proliferator-activated receptor pan-agonist bezafibrate suppresses microvascular inflammatory responses of retinal endothelial cells and vascular endothelial growth factor production in retinal pigmented epithelial cells. Int Immunopharmacol. 2017 Nov;52:70-76.