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Dapagliflozin BMS-512148

Dapagliflozin BMS-512148 461432-26-8
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Chemical Information
Product name:Dapagliflozin BMS-512148 Purity:98% min
CAS NO:461432-26-8 Solubility:10 mM in DMSO
Molecular Formula:C21H25ClO6 Package:Package according to customer requirements
Molecular Weight:408.873 Storage:Store at -20℃
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Remarks
Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.
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