Plecanatide is a structural analog of human uroguanylin, and similarly to uroguanylin, plecanatide functions as a guanylate cyclase-C (GC-C) agonist. Both plecanatide and its active metabolite bind to GC-C and act locally on the luminal surface of the intestinal epithelium. Activation of GC-C results in an increase in both intracellular and extracellular concentrations of cyclic guanosine monophosphate (cGMP).
Related Products:
Linaclotide; Carbetocin; Octreotide acetate; Terlipressin; Cetrorelix; Desmopressin; Desmopressin acetate; Degarelix; Goserelin acetate; Ganirelix Acetate; Abarelix; GLP-1 (7-37); Semaglutide