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Eltrombopag 496775-61-2
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Chemical Information
Product name:Eltrombopag Purity:98% min
CAS NO:496775-61-2 Solubility:10 mM in DMSO
Molecular Formula:C25H22N4O4 Package:Package according to customer requirements
Molecular Weight:442.467 Storage:Store at -20℃
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Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was approved by FDA in November 20, 2008.

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