AMG9810

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：AMG9810	Purity：99% min
CAS NO：545395-94-6	Solubility：DMSO : ≥ 33 mg/mL (97.80 mM)
Molecular Formula：C₂₁H₂₃NO₃	Package：Package according to customer requirements
Molecular Weight：337.412	Storage：2-8°C

Quality control

COA

Remarks

AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1). Additionally, it has been shown to compete with other modes of TRPV1 activation, including proton, heat, and the endogenous ligands: anandamide, N-arachidonyl dopamine and oleoyldopamine.

Properties

Density:1.175g/cm3

Boiling Point:512.5ºC at 760 mmHg

Flash Point:263.8ºC

Refractive Index:1.617

TRP Channel Inhibitors Related Products:

TRPM8 Antagonist 2; SB366791; Rosiglitazone; HC-030031; Clemizole; Clemizole hydrochloride; AMG-517

References

[1]. Gavva NR, et al. AMG9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. J Pharmacol Exp Ther. 2005 Apr;313(1):474-84.

[2]. Li S, et al. TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling. Carcinogenesis. 2011 May;32(5):779-85.