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Product :

Dapansutrile

Dapansutrile  54863-37-5
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Chemical Information
Product name:Dapansutrile Purity:98% min
CAS NO:54863-37-5 Solubility:DMSO : ≥ 125 mg/mL (938.65 mM)
Molecular Formula:C4H7NO2S Package:Package according to customer requirements.
Molecular Weight:133.169 Storage:Store in a cool, dry area.
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Remarks

Dapansutrile, also known as OLT1177, is an anti-inflammatory, analgesic drug candidate. Dapansutrile is a β-sulfonyl nitrile inhibitor of the NLRP3 inflammasome that inhibits the release of IL-1β and decreases caspase-1 levels in LPS-stimulated J774A. murine macrophages, human monocyte derived macrophages (HMDMs), and primary human blood neutrophils without affecting TNF-α release.

 

Synonyms:

1-cyano-2-methylisoindole;

3-methanesulfonylpropionitrile;

2-methyl-2H-isoindole-1-carbonitrile;

2H-Isoindole-1-carbonitrile,2-methyl;

3-(methylsulfonyl)propionitrile;

1-cyano-2-methylsulphonylethane;

 

 

 

 

NLRP3 Inhibitors Related Products:

MCC950 Sodium

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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