Buserelin

Buserelin is a Gonadotropin-releasing hormone agonist (GnRH agonist). The drug's effects are dependent on the frequency and time course of administration. GnRH is released in a pulsatile fashion in the postpubertal adult. Initial interaction of any GnRH agonist, such as buserelin, with the GnRH receptor induces release of FSH and LH by gonadotrophes.

Chemical Properties:

alpha: D20 -40.4° (c = 1 in dimethylacetamide)

Boiling point: 845.19°C (rough estimate)

density: 1.0711 (rough estimate)

refractive index: 1.6200 (estimate)

pka: 9.82±0.15(Predicted)

Related Prodcuts:

Dynorphin A (1-13); Deslorelin; Gonadorelin; Gonadorelin acetate; Sermorelin; Sermorelin Acetate; Etelcalcetide; DSIP; Lixisenatide; Angiotensin acetate; Epithalone; Cilengitide; Cilengitide trifluoroacetate; Tesamorelin; Selank; ACTH (1-39) Seractide; Ipamorelin

1: Harada T, Taniguchi F. Dienogest: a new therapeutic agent for the treatment of endometriosis. Womens Health (Lond Engl). 2010 Jan;6(1):27-35. Review. PubMed PMID: 20001868.

2: Thitaram C, Pongsopawijit P, Chansitthiwet S, Brown JL, Nimtragul K, Boonprasert K, Homkong P, Mahasawangkul S, Rojanasthien S, Colenbrander B, van der Weijden GC, van Eerdenburg FJ. Induction of the ovulatory LH surge in Asian elephants (Elephas maximus): a novel aid in captive breeding management of an endangered species. Reprod Fertil Dev. 2009;21(5):672-8. PubMed PMID: 19486604.