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Product :

HA14-1

HA14-1 65673-63-4
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Chemical Information
Product name:HA14-1 Purity:98% min
CAS NO:65673-63-4 Solubility:DMSO : ≥ 50 mg/mL (122.18 mM)
Molecular Formula:C17H17BrN2O5 Package:Packaging according to customer requirements
Molecular Weight:409.231 Storage:Store at -20℃
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Remarks

HA14-1 is a potent Bcl-2 inhibitor with potential anticancer activity. HA14-1 induces apoptosis in various human cancer cells. HA14-1 suppressed NF-kappaB activation through inhibition of phosphorylation and degradation of IkappaBalpha. This inhibition was correlated with suppression of NF-kappaB-dependent gene products (c-myc, cyclin D1, cox-2, and IAP-1). Additionally, HA14-1 also markedly sustained TNF-alpha-mediated JNK activation.

 

 

 

Bcl-2 Inhibitors Related Products:

ABT-737; Obatoclax Mesylate; Venetoclax; S63845; UMI-77; Mifepristone; Navitoclax 

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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